Leishmania donovaniand Cutaneous Leishmaniasis, Sri Lanka

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Leishmania donovani and Cutaneous Leishmaniasis, Sri Lanka

To investigate the relationship of cutaneous leishmaniasis isolates from Sri Lanka to known species, we performed DNA sequencing and microsatellite analyses. We identified Leishmania donovani as the agent of Sri Lanka cutaneous leishmaniasis and showed that these parasites are closely related to those causing visceral leishmaniasis in the Indian subcontinent.

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Cutaneous Leishmaniasis, Sri Lanka

Cutaneous leishmaniasis (CL) is an emerging disease in Sri Lanka. Of 116 patients with clinical symptoms suggestive of CL, 86 were confirmed positive for Leishmania donovani. Most patients had single dry lesions, usually on the face. Patients were from 5 of the 7 agroclimatic zones in Sri Lanka.

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Evidence for Seroprevalence in Human Localized Cutaneous Leishmaniasis Caused by Leishmania donovani in Sri Lanka

Visceral leishmaniasis (VL) is considered as a major health threat in the Indian subcontinent. Leishmania donovani, a usually visceralizing species, causes cutaneous leishmaniasis (CL) in Sri Lanka. However, visceralizing potential of the local L. donovani is not yet fully understood. This project studied the seroprevalence of local CL by using an in-house ELISA. An IgG-based ELISA using crude ...

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Leishmania donovani is the agent of cutaneous leishmaniasis in Sri Lanka

DNA sequencing and microsatellite analyses were performed to investigate the relationship of Sri Lankan cutaneous leishmaniasis isolates to known species of Leishmania. This identified L. donovani as the agent of Sri Lankan cutaneous leishmaniasis, and showed these parasites are closely related to those causing visceral leishmaniasis in the Indian subcontinent.

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A histopathological study of cutaneous leishmaniasis in Sri Lanka.

UNLABELLED INTRODUCTION; Cutaneous leishmaniasis is endemic in Sri Lanka. The immunopathogenesis of these lesions in Sri Lankans has not been documented. OBJECTIVES To classify skin lesions into histological groups, to assess parasitic load, density of each inflammatory cell type and necrosis and to characterise the lymphocytic reaction in cutaneous leishmaniasis in comparison to leprosy. M...

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ژورنال

عنوان ژورنال: Emerging Infectious Diseases

سال: 2007

ISSN: 1080-6040,1080-6059

DOI: 10.3201/eid1303.060242